Antigen

Antigen Class

ATAC-Seq

Antigen

ATAC-Seq

Cell type

Cell type Class

Blood

Cell type

Th17 Cells

MeSH Description

A subset of helper-effector T-lymphocytes which synthesize and secrete INTERLEUKINS IL-17; IL-17F; and IL-22. These cytokines are involved in host defenses and tissue inflammation in autoimmune diseases.

Sample

source_name

Th17 cells

strain

C57BL/6

genotype

STAT3 fl/fl -CD4cre

age

3 days in vitro

tissue

Spleen+Lymph nodes

cell type

Th17 cells

Sequenced DNA Library

library_strategy

ATAC-seq

library_source

GENOMIC

library_selection

other

library_construction_protocol

DNA were extracted using TruePrep DNA Library Prep Kit V2 for Illumina. DNA libraries were constructed with TruePrep DNA Library Prep Kit V2 and TruePrep Index Kit V2 for Illumina.

Sequencing Platform

instrument_model

HiSeq X Ten

mm10

Number of total reads

29260987

Reads aligned (%)

74.5

Duplicates removed (%)

48.9

Number of peaks

2112 (qval < 1E-05)

mm9

Number of total reads

29260987

Reads aligned (%)

74.4

Duplicates removed (%)

48.8

Number of peaks

2086 (qval < 1E-05)