Antigen

Antigen Class

ATAC-Seq

Antigen

ATAC-Seq

Cell type

Cell type Class

Blood

Cell type

Mast Cells

MeSH Description

Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR.

Sample

source_name

Tonsilitis patient

cell type

Tonsillar mast cells

passages

fresh

Sequenced DNA Library

library_strategy

ATAC-seq

library_source

GENOMIC

library_selection

other

library_construction_protocol

Omni-ATAC-seq libraries were prepared as previously described (Corces 2017, Nature Methods). Paired-end - Illumina; Omni-ATAC-seq

Sequencing Platform

instrument_model

NextSeq 500

hg38

Number of total reads

48714192

Reads aligned (%)

98.4

Duplicates removed (%)

3.0

Number of peaks

37145 (qval < 1E-05)

hg19

Number of total reads

48714192

Reads aligned (%)

97.5

Duplicates removed (%)

3.4

Number of peaks

37898 (qval < 1E-05)