Cell lysates were treated with Tn5 transposease and DNA was purified following the protocol outlined in Buenrostro et al. 2015 Curr. Protoc. Mol. Biol. 109:21.29.1-9 and Buenrostro et al 2013 Nat. Med. 10(12):1213-8. Libraries were generated following the following the protocol outlined in Buenrostro et al. 2015 Curr. Protoc. Mol. Biol. 109:21.29.1-9 and Buenrostro et al 2013 Nat. Med. 10(12):1213-8.