Genomic DNA was extracted using the QIAquick PCR Purification Kit (Qiagen). RNA was isolated via RNeasy Plus Mini Kit (Qiagen). ChIP libraries were generate using the Ovation Ultralow Library Systems V2 (NuGEN). ATAC libraries were generated using the Nextera DNA Sample Prep Kit (Illumina). RNA libraries were generated using the Ovation RNA-Seq System V2 (NuGEN).