ChIP experiments were performed with formaldehyde cross-linked cells using anti-BRD4 antibody (Bethyl #A301-985A). Input and ChIP samples were processed using Diagenode iDeal ChIP-seq for Transcription Factors Kit. Illumina TruSeq ChIP Sample Prep Kit, using 10 ng of input material. RNA: Trizol/CHCl3; ChIP: formaldedhyde cross-linking followed by Diagenode iDeal ChIP-seq for Transcription Factors Kit. Also see SAMPLES section. RNA-seq: Agilent SureSelect Strand-Specific mRNA Library Preparation Protocol; ChIP-seq: Illumina TruSeq ChIP Sample Prep Kit. Also see SAMPLES section.