Cells were crosslinked in 1% formaldehyde for 10 minutes. Cells were then washed in PBS (x2) and resuspended in lysis buffer (10mM Tris,100mM NaCl, 1mM EDTA, 0.5mM EGTA, 0.1% Na-Deoxycholate, 0.5% N-lauroylsarcosine) to extract chromatin. Lysates were then sonicated using a BioRuptor, centrifuged to pellet cellular debris, and immunoprecipitated. After reversing crosslinks, libraries were prepped using the NEBnext DNA Library Prep Kit (NEB, E7370L). Adapter ligated DNA was size selected and purified using AMPure XP beads (Beckman Coulter, A63881) before sequencing.