Antigen

Antigen Class

Histone

Antigen

H3K27ac

Cell type

Cell type Class

Muscle

Cell type

Rhabdomyosarcoma

MeSH Description

A malignant solid tumor arising from mesenchymal tissues which normally differentiate to form striated muscle. It can occur in a wide variety of sites. It is divided into four distinct types: pleomorphic, predominantly in male adults; alveolar (RHABDOMYOSARCOMA, ALVEOLAR), mainly in adolescents and young adults; embryonal (RHABDOMYOSARCOMA, EMBRYONAL), predominantly in infants and children; and botryoidal, also in young children. It is one of the most frequently occurring soft tissue sarcomas and the most common in children under 15. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p2186; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1647-9)

Sample

source_name

RMS cell line, mutant HRAS

antibody

H3K27ac, Active Motif (cat39133, lot 31814008 pAb)

enrichment target

H3K27ac

target function

Active enhancers

time

48 hr

treatment

Trametinib 100nM

Sequenced DNA Library

library_name

ERROR: cannot retrieve data from NCBI: too many requests

library_strategy

ERROR: cannot retrieve data from NCBI: too many requests

library_source

ERROR: cannot retrieve data from NCBI: too many requests

library_selection

ERROR: cannot retrieve data from NCBI: too many requests

library_construction_protocol

ERROR: cannot retrieve data from NCBI: too many requests

Sequencing Platform

instrument_model

ERROR: cannot retrieve data from NCBI: too many requests

cycle_sequence

ERROR: cannot retrieve data from NCBI: too many requests

cycle_count

ERROR: cannot retrieve data from NCBI: too many requests

flow_sequence

ERROR: cannot retrieve data from NCBI: too many requests

flow_count

ERROR: cannot retrieve data from NCBI: too many requests

key_sequence

ERROR: cannot retrieve data from NCBI: too many requests

hg38

Number of total reads

14509970

Reads aligned (%)

97.5

Duplicates removed (%)

7.7

Number of peaks

14309 (qval < 1E-05)

hg19

Number of total reads

14509970

Reads aligned (%)

97.0

Duplicates removed (%)

8.7

Number of peaks

14230 (qval < 1E-05)