Antigen

Antigen Class

TFs and others

Antigen

Ep300

Cell type

Cell type Class

Blood

Cell type

Th1 Cells

MeSH Description

A subset of helper-inducer T-lymphocytes which synthesize and secrete INTERLEUKIN-2; INTERFERON-GAMMA; and INTERLEUKIN-12. Due to their ability to kill antigen-presenting cells and their lymphokine-mediated effector activity, Th1 cells are associated with vigorous delayed-type hypersensitivity reactions.

Sample

source_name

primary CD4+ T cells from spleen and lymph nodes

strain

C57BL/6J

genotype/variation

wild type

cell type

in vitro polarized T helper2 cells for 5 days with Gata3 overexpression

passages

Gata3 overexpression vector was made in Th2 cells.

chip antibody

anti-p300

Sequenced DNA Library

library_strategy

ChIP-Seq

library_source

GENOMIC

library_selection

ChIP

Sequencing Platform

instrument_model

Illumina Genome Analyzer II

mm10

Number of total reads

29328854

Reads aligned (%)

96.0

Duplicates removed (%)

25.9

Number of peaks

54327 (qval < 1E-05)

mm9

Number of total reads

29328854

Reads aligned (%)

95.9

Duplicates removed (%)

26.0

Number of peaks

54296 (qval < 1E-05)