GSM935399: Harvard ChipSeq MCF10A-Er-Src 4OHTAM 1uM 12hr STAT3 Harvard Control
Sample information curated by ChIP-Atlas
Antigen
Antigen Class
TFs and others
Antigen
STAT3
Cell type
Cell type Class
Breast
Cell type
MCF 10A
Primary Tissue
Breast
Tissue Diagnosis
Fibrocystic Disease
Attributes by original data submitter
Sample
source_name
MCF10A-Er-Src
biomaterial_provider
Struhl laboratory
lab
Harvard
lab description
Struhl - Harvard University
datatype
ChipSeq
datatype description
Chromatin IP Sequencing
cell
MCF10A-Er-Src
cell organism
human
cell description
mammary gland, non-tumorigenic epithelial, inducible cell line, derived from the MCF-10A parental cells and contain ER-Src, a derivative of the Src kinase oncoprotein (v-Src) that is fused to the ligand-binding domain of the estrogen receptor (ER)
cell karyotype
normal
cell lineage
ectoderm
cell sex
F
treatment
4OHTAM_1uM_12hr
treatment description
12 hours with 1 uM 4-hydroxytamoxifen dissolved in ethanol (Struhl)
antibody
STAT3
antibody antibodydescription
Rabbit polyclonal; epitope mapping at the C-terminus of Stat3 of mouse origin. Antibody Target: STAT3
antibody targetdescription
Member of STAT family. After phosphorylation in response to cytokines and growth factors (including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2), forms homo- or heterodimers that translocate to nucleus and activate transcription. Activates expression of a variety of genes with roles in processes such as cell growth and apoptosis.