Antigen

Antigen Class

TFs and others

Antigen

YY1

Cell type

Cell type Class

Neural

Cell type

SK-N-SH

Primary Tissue

Brain

Tissue Diagnosis

Neuroblastoma

Sample

source_name

SK-N-SH_RA

biomaterial_provider

ATCC

datatype

ChipSeq

datatype description

Chromatin IP Sequencing

cell description

neuroblastoma cell line, treatment: differentiated with retinoic acid, (Biedler, et al. Morphology and Growth, Tumorigenicity, and Cytogenetics of Human Neuroblastoma Cells in Continuous Culture. Cancer Research 33, 2643-2652, November 1973.)

antibody antibodydescription

Rabbit polyclonal IgG, epitope mapping at the C-terminus of YY1 of human origin. Antibody Target: YY1

antibody targetdescription

YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1

antibody vendorname

Santa Cruz Biotechnology

antibody vendorid

sc-281

controlid

SL2905

labexpid

SL3639,SL3640

replicate

1,2

softwareversion

MACS

antibody antibodydescription

Rabbit polyclonal IgG, epitope mapping at the C-terminus of YY1 of human origin

antibody targetdescription

YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1

antibody vendorname

Santa Cruz Biotech

antibody vendorid

sc-281

treatment

None

treatment description

No special treatment or protocol applies

protocol

v041610.2

protocol description

2x10^7 cells, fragmentation by probe-in sonicator, one 15-cycle round of PCR (Myers)

controlid

SL2905

labexpid

SL3639

replicate

1

replicate description

tier 1

Sequenced DNA Library

library_name

GSM803498: HudsonAlpha_ChipSeq_SK-N-SH_RA_YY1_(SC-281)_v041610.2

library_strategy

ChIP-Seq

library_source

GENOMIC

library_selection

ChIP

Sequencing Platform

instrument_model

Illumina Genome Analyzer

hg38

Number of total reads

67642201

Reads aligned (%)

90.8

Duplicates removed (%)

12.7

Number of peaks

40710 (qval < 1E-05)

hg19

Number of total reads

67642201

Reads aligned (%)

90.3

Duplicates removed (%)

14.0

Number of peaks

40534 (qval < 1E-05)