Antigen

Antigen Class

TFs and others

Antigen

Mafa

Cell type

Cell type Class

Pancreas

Cell type

Islets of Langerhans

MeSH Description

Irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the PANCREAS among the exocrine acini. Each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. There are four major cell types. The most abundant beta cells (50-80%) secrete INSULIN. Alpha cells (5-20%) secrete GLUCAGON. PP cells (10-35%) secrete PANCREATIC POLYPEPTIDE. Delta cells (~5%) secrete SOMATOSTATIN.

Sample

source_name

Pancreatic islets_MafA

strain

CD-1

age

8-10 week old

tissue/cell type

hand-picked pancreatic islets

chip antibody

MafA (Abcam ab17976 lot 950583)

Sequenced DNA Library

library_name

GSM751037: MafA_ChIPSeq

library_strategy

ChIP-Seq

library_source

GENOMIC

library_selection

ChIP

Sequencing Platform

instrument_model

Illumina Genome Analyzer II

mm10

Number of total reads

188448693

Reads aligned (%)

6.2

Duplicates removed (%)

58.6

Number of peaks

14639 (qval < 1E-05)

mm9

Number of total reads

188448693

Reads aligned (%)

6.2

Duplicates removed (%)

58.8

Number of peaks

14472 (qval < 1E-05)