Antigen

Antigen Class

TFs and others

Antigen

Stat3

Cell type

Cell type Class

Blood

Cell type

Th17 Cells

MeSH Description

A subset of helper-effector T-lymphocytes which synthesize and secrete INTERLEUKINS IL-17; IL-17F; and IL-22. These cytokines are involved in host defenses and tissue inflammation in autoimmune diseases.

Sample

source_name

in vitro polarized Th17 T cells

strain

Stat3fl/fl FoxP3-GFP<STAT3 wild type>

cell type

WT-Th17 polazied T cells from naive

passages

mouse primary T cells cultured in vitro for 3 days and restimulated with IL6

chip antibody

Phospho-STAT3(Ser727)

antibody manufacturer

Cell Signaling

antibody catalog number

9134

Sequenced DNA Library

library_name

GSM540722: Stat3fl/fl FoxP3-GFP<STAT3 wild type>, STAT3-ChIPSeq

library_strategy

ChIP-Seq

library_source

GENOMIC

library_selection

ChIP

Sequencing Platform

instrument_model

Illumina Genome Analyzer

mm10

Number of total reads

18052106

Reads aligned (%)

84.5

Duplicates removed (%)

19.4

Number of peaks

14109 (qval < 1E-05)

mm9

Number of total reads

18052106

Reads aligned (%)

84.4

Duplicates removed (%)

19.5

Number of peaks

14191 (qval < 1E-05)