ChIP was performed using SimpleChip Enzymatic Chromatin IP Kit (Cell Signaling Technology) according to the manufacturer's protocol. For ChIP assays 10 µg of goat antibody against SNAIL (R&D Systems, cat. AB-108-C) was used. After immunoprecipitation, the DNA was isolated using spin columns from the kit. Input sample was also analyzed. Chip-Seq analysis was performed using the Intelliseq sp. z o. o. (Cracow, Poland) company service in cooperation with Novogene Co., Lt d using Illumina high-throughput sequencer. RNA libraries were prepared for sequencing using standard Illumina protocols. Paired-end sequencing libraries were sequenced by Illumina high-throughput sequencer by the Novogene company.