Lysates were clarified from sonicated nuclei. The chromatin solution was immunoprecipitated with either YAP antibody or TAZ antibody. The immunoprecipitations were performed using Pierce ChIP-grade Protein G magnetic beads (Thermo Fisher Scientific). Reverse cross-linking and DNA purification was performed by ChIP DNA Clean & Concentrator kit (Zymo Research, USA). Libraries were prepared as described in Blecher-Gonen et al., Nat Protoc, 2013. 8(3): p. 539-54.