Antigen

Antigen Class

Input control

Antigen

Input control

Cell type

Cell type Class

Blood

Cell type

Multiple Myeloma

MeSH Description

A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.

Sample

source_name

multiple myeloma

tissue

peripheral blood

cell type

B lymphoblast

antibody

none

Sequenced DNA Library

library_strategy

ChIP-Seq

library_source

GENOMIC

library_selection

ChIP

library_construction_protocol

Lysates were clarified from sonicated cell and histone-DNA complexes were isolated with antibody. Libraries were prepared for sequencing using standard Illumina protocols

Sequencing Platform

instrument_model

Illumina MiSeq

hg38

Number of total reads

8754946

Reads aligned (%)

99.0

Duplicates removed (%)

1.1

Number of peaks

445 (qval < 1E-05)

hg19

Number of total reads

8754946

Reads aligned (%)

98.2

Duplicates removed (%)

2.3

Number of peaks

568 (qval < 1E-05)