Antigen

Antigen Class

DNase-seq

Antigen

DNase-Seq

Cell type

Cell type Class

Placenta

Cell type

Trophoblasts

MeSH Description

Trophoblasts with multinuclear cytoplasm and undefined cellular structures. Syncytiotrophoblasts secrete proteolytic enzymes that erode the ENDOMETRIUM for EMBRYO IMPLANTATION. They also produce steroid, peptide, and protein hormones (PLACENTAL HORMONES).

Sample

dev stage

fetal

cell type

trophoblast cell

sex

not collected

sample type

primary cell

donor ID

ENCDO623MQT

age

23 week

lab

John Stamatoyannopoulos, UW

Sequenced DNA Library

library_strategy

DNase-Hypersensitivity

library_source

GENOMIC

library_selection

DNase

library_construction_protocol

other: https://www.encodeproject.org/documents/926174f5-d14c-4e77-bc52-5517b56daac0/@@download/attachment/Culturedcells_SOP_nuclei_DNase_crosslink_RNA_V1.pdf

Sequencing Platform

instrument_model

NextSeq 500

hg38

Number of total reads

167365438

Reads aligned (%)

67.9

Duplicates removed (%)

47.5

Number of peaks

137063 (qval < 1E-05)

hg19

Number of total reads

167365438

Reads aligned (%)

67.6

Duplicates removed (%)

47.9

Number of peaks

136298 (qval < 1E-05)