Antigen

Antigen Class

Histone

Antigen

H3K27ac

Cell type

Cell type Class

Blood

Cell type

Plasma Cells

MeSH Description

Specialized forms of antibody-producing B-LYMPHOCYTES. They synthesize and secrete immunoglobulin. They are found only in lymphoid organs and at sites of immune responses and normally do not circulate in the blood or lymph. (Rosen et al., Dictionary of Immunology, 1989, p169 & Abbas et al., Cellular and Molecular Immunology, 2d ed, p20)

Sample

source_name

Chromatin IP against H3K27ac in MM.1S (500 nM JQ1) for 12022011_B0A1WABXX*

diagnosis

Multiple myeloma

chip antibody

H3K27Ac

antibody catalog number

Abcam AB4729

cell type

Plasma cell

treatment duration

24 hr

treatment concentration

500nM

treatment drug

JQ1

Sequenced DNA Library

library_strategy

ChIP-Seq

library_source

GENOMIC

library_selection

ChIP

Sequencing Platform

instrument_model

Illumina HiSeq 2000

hg38

Number of total reads

21195109

Reads aligned (%)

95.0

Duplicates removed (%)

2.5

Number of peaks

16505 (qval < 1E-05)

hg19

Number of total reads

21195109

Reads aligned (%)

94.4

Duplicates removed (%)

3.0

Number of peaks

16548 (qval < 1E-05)