Cross-linked cell pellets were lyzed, nuclei extracted, sonicated, immunoprecipitated, washed, reverse cross-link and column purified. Barcoded ChIP-seq libraries were made from ChIP DNA using the NuGen Ovation Ultralow DR or Diagenode Microplex Kit, checked for adapter artifacts by Agilent Bioanalyzer using DNA high sensitivity reagents and chips, and quantified by qPCR using an Illumina Library Quantification kit (KAPA Biosystems)