Antigen

Antigen Class

DNase-seq

Antigen

DNase-Seq

Cell type

Cell type Class

Blood

Cell type

Th17 Cells

MeSH Description

A subset of helper-effector T-lymphocytes which synthesize and secrete INTERLEUKINS IL-17; IL-17F; and IL-22. These cytokines are involved in host defenses and tissue inflammation in autoimmune diseases.

Sample

source_name

Th17

biomaterial_provider

John Stamatoyannopoulos

lab

UW

lab description

Stamatoyannopoulous - University of Washington

datatype

DnaseDgf

datatype description

DNase Digital Footprinting

cell

Th17

cell organism

human

cell description

T helper cells expressing IL-17, primary pheresis of single normal subject

cell karyotype

normal

cell lineage

mesoderm

cell sex

B

treatment

None

treatment description

No special treatment or protocol applies

labexpid

DS11039

labversion

Hotspot-v5.2,lmax-v1.0,WindowDensity-bin20-win+/-75

Sequenced DNA Library

library_name

GSM1014541: UW_DnaseDgf_Th17

library_strategy

DNase-Hypersensitivity

library_source

GENOMIC

library_selection

DNase

Sequencing Platform

instrument_model

Illumina HiSeq 2000

hg38

Number of total reads

205484237

Reads aligned (%)

71.4

Duplicates removed (%)

36.5

Number of peaks

60801 (qval < 1E-05)

hg19

Number of total reads

205484237

Reads aligned (%)

70.7

Duplicates removed (%)

38.4

Number of peaks

60183 (qval < 1E-05)