Antigen

Antigen Class

DNase-seq

Antigen

DNase-Seq

Cell type

Cell type Class

Blood

Cell type

Th1 Cells

MeSH Description

A subset of helper-inducer T-lymphocytes which synthesize and secrete INTERLEUKIN-2; INTERFERON-GAMMA; and INTERLEUKIN-12. Due to their ability to kill antigen-presenting cells and their lymphokine-mediated effector activity, Th1 cells are associated with vigorous delayed-type hypersensitivity reactions.

Sample

source_name

Th1_Wb33676984

biomaterial_provider

John Stamatoyannopoulos

lab

UW

lab description

Stamatoyannopoulous - University of Washington

datatype

DnaseDgf

datatype description

DNase Digital Footprinting

cell

Th1_Wb33676984

cell organism

human

cell description

Th1 cells in vivo isolation

cell karyotype

normal donor is Asian, female 26 year old, primary pheresis of single normal subject

cell lineage

mesoderm

cell sex

F

treatment

None

treatment description

No special treatment or protocol applies

labexpid

DS18015

labversion

Hotspot-v5.2,lmax-v1.0,WindowDensity-bin20-win+/-75

Sequenced DNA Library

library_name

GSM1014540: UW_DnaseDgf_Th1_Wb33676984

library_strategy

DNase-Hypersensitivity

library_source

GENOMIC

library_selection

DNase

Sequencing Platform

instrument_model

Illumina HiSeq 2000

hg38

Number of total reads

195616275

Reads aligned (%)

94.7

Duplicates removed (%)

31.1

Number of peaks

80498 (qval < 1E-05)

hg19

Number of total reads

195616275

Reads aligned (%)

94.0

Duplicates removed (%)

32.7

Number of peaks

79564 (qval < 1E-05)