GSM1010835: HudsonAlpha ChipSeq SK-N-SH Max v042211.1
Sample information curated by ChIP-Atlas
TFs and others
Cell type Class
Attributes by original data submitter
Rabbit polyclonal IgG, epitope mapping at the C-terminus of Max of human origin. Antibody Target: Max
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown (RefSeq).
Santa Cruz Biotechnology
neuroblastoma, newly promoted to tier 2: not in 2011 analysis, the SK-N-SH line was established from a neuroblastoma in a 4 year old individual.
Chromatin IP Sequencing
Myers - Hudson Alpha Institute for Biotechnology
Faster ChIP protocol & AMpure XP size selection for ChIP-seq (Myers)