Sample information curated by ChIP-Atlas

Antigen

Antigen Class
TFs and others
Antigen
CHD1

Cell type

Cell type Class
Blood
Cell type
K-562
Primary Tissue
Blood
Tissue Diagnosis
Leukemia Chronic Myelogenous

Attributes by original data submitter

Sample

source_name
K562
biomaterial_provider
ATCC
datatype
ChipSeq
datatype description
Chromatin IP Sequencing
antibody antibodydescription
Rabbit Polyclonal Antigen Affinity Purified, Unconjugated, Liquid. Antibody Target: CHD1
antibody targetdescription
CHD1 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD1 has been shown to interact with the transcriptional corepressor NCoR and histone deacetylase 1 indicating a role in transcriptional regulation. CHD1 has also been shown to interact with the Paf1 complex and Rtf1 implicating an additional role in transcriptional elongation. Alternate names for CHD1 include chromodomain-helicase-DNA-binding protein 1, ATP-dependent helicase CHD1, and DKFZp686E2337.
antibody vendorname
Bethyl Laboratories
antibody vendorid
A301-218A
controlid
wgEncodeEH000052
replicate
1,2
softwareversion
ScriptureVPaperR3
cell sex
F
antibody
CHD1_(A301-218A)
antibody antibodydescription
Rabbit Polyclonal Antigen Affinity Purified, Unconjugated, Liquid. Antibody Target: CHD1
antibody targetdescription
CHD1 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD1 has been shown to interact with the transcriptional corepressor NCoR and histone deacetylase 1 indicating a role in transcriptional regulation. CHD1 has also been shown to interact with the Paf1 complex and Rtf1 implicating an additional role in transcriptional elongation. Alternate names for CHD1 include chromodomain-helicase-DNA-binding protein 1, ATP-dependent helicase CHD1, and DKFZp686E2337.
antibody vendorname
Bethyl Laboratories
antibody vendorid
A301-218A
treatment
None
treatment description
No special treatment or protocol applies
control
std
control description
Standard input signal for most experiments.
controlid
K562/Input/std
softwareversion
ScriptureVPaperR3

Sequenced DNA Library

library_name
GSM1003575: Broad_ChipSeq_K562_CHD1_(A301-218A)
library_strategy
ChIP-Seq
library_source
GENOMIC
library_selection
ChIP

Sequencing Platform

instrument_model
Illumina Genome Analyzer

hg19

Number of total reads
67277657
Reads aligned (%)
56.9
Duplicates removed (%)
33.1
Number of peaks
7265 (qval < 1E-05)

hg38

Number of total reads
67277657
Reads aligned (%)
58.8
Duplicates removed (%)
31.4
Number of peaks
7435 (qval < 1E-05)

Base call quality data from DBCLS SRA