Mouse monoclonal IgG, raised against recombinant CBX3 of human origin. Antibody Target: CBX3
antibody targetdescription
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.
antibody vendorname
Santa Cruz Biotechnology
antibody vendorid
sc-101004
controlid
wgEncodeEH000052
replicate
1
softwareversion
ScriptureVPaperR3
cell sex
F
antibody
CBX3_(SC-101004)
antibody antibodydescription
Mouse monoclonal IgG, raised against recombinant CBX3 of human origin. Antibody Target: CBX3
antibody targetdescription
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.