The nuclear receptor corepressor protein (NCoR) mediates gene repression by interacting with nuclear receptors. NCoR mediates repression by associating with SIN3A/B and the histone deacetylases, HDAC1 and HDAC2, and promoting the formation of repressive chromatin structures.
The nuclear receptor corepressor protein (NCoR) mediates gene repression by interacting with nuclear receptors. NCoR mediates repression by associating with SIN3A/B and the histone deacetylases, HDAC1 and HDAC2, and promoting the formation of repressive chromatin structures.