Antigen

Antigen Class

TFs and others

Antigen

CUX1

Cell type

Cell type Class

Blood

Cell type

GM12878

Tissue

blood

Lineage

mesoderm

Description

B-lymphocyte, lymphoblastoid, International HapMap Project - CEPH/Utah - European Caucasion, Epstein-Barr Virus

Sample

source_name

GM12878

biomaterial_provider

GM12878

lab

Stanford

lab description

Snyder - Stanford University

datatype

ChipSeq

datatype description

Chromatin IP Sequencing

cell

GM12878

cell organism

human

cell description

B-lymphocyte, lymphoblastoid, International HapMap Project - CEPH/Utah - European Caucasion, Epstein-Barr Virus

cell karyotype

normal

cell lineage

mesoderm

cell sex

F

treatment

None

treatment description

No special treatment or protocol applies

antibody

CDP_(sc-6327)

antibody antibodydescription

CDP (C-20) is an affinity purified goat polyclonal antibody raised against a peptide mapping at the C-terminus of CDP of mouse origin.

antibody targetdescription

CDP (for CCAAT displacement protein) was identified as a repressor for tran- scription of developmentally regulated genes. It is a homeodomain protein that appears to compete with transcriptional activating proteins for binding to the promoter regions of various genes. CDP contains three cut repeats which function as DNA binding domains. It has been demonstrated that cut repeat domains have the capacity to bind to DNA in conjunction with or independently of homeodomain DNA binding. CDP has been shown to be the DNA-binding subunit of the HiNF-D complex, which contains cyclin A, Cdc2 and an Rb-related protein in addition to CDP. Histone expression is required for the transition to S phase in the cell cycle. The HiNF-D complex regulates the transcription of Histone H4, H3 and H1 genes, allowing cells to progress from G1 to S phase.

antibody vendorname

Santa Cruz Biotechnology

antibody vendorid

sc-6327

control

IgG-mus

control description

Input signal from Normal Mouse IgG ChIP-seq.

control

IgG-mus

control description

Input signal from Normal Mouse IgG ChIP-seq.

controlid

wgEncodeEH000706

labversion

PeakSeq1.0

Sequenced DNA Library

library_name

GSM1003604: Stanford_ChipSeq_GM12878_CDP_(sc-6327)_IgG-mus

library_strategy

ChIP-Seq

library_source

GENOMIC

library_selection

ChIP

Sequencing Platform

instrument_model

Illumina Genome Analyzer

hg38

Number of total reads

62492520

Reads aligned (%)

90.4

Duplicates removed (%)

7.5

Number of peaks

6230 (qval < 1E-05)

hg19

Number of total reads

62492520

Reads aligned (%)

89.3

Duplicates removed (%)

8.5

Number of peaks

6235 (qval < 1E-05)