Antigen

Antigen Class

TFs and others

Antigen

Tbx21

Cell type

Cell type Class

Blood

Cell type

Th1 Cells

MeSH Description

A subset of helper-inducer T-lymphocytes which synthesize and secrete INTERLEUKIN-2; INTERFERON-GAMMA; and INTERLEUKIN-12. Due to their ability to kill antigen-presenting cells and their lymphokine-mediated effector activity, Th1 cells are associated with vigorous delayed-type hypersensitivity reactions.

Sample

source_name

Tbet -/- Th1 cells

antibody

T-bet (Lab produced (Szabo et al., Nature 2000))

cell type

Th1

cell number

100000000

genotype

Tbet_KO

Sequenced DNA Library

library_strategy

ChIP-Seq

library_source

GENOMIC

library_selection

ChIP

Sequencing Platform

instrument_model

Illumina Genome Analyzer IIx

mm10

Number of total reads

56006530

Reads aligned (%)

52.1

Duplicates removed (%)

36.4

Number of peaks

1970 (qval < 1E-05)

mm9

Number of total reads

56006530

Reads aligned (%)

51.9

Duplicates removed (%)

36.5

Number of peaks

2068 (qval < 1E-05)