leukemia, "The continuous cell line K-562 was established by Lozzio and Lozzio from the pleural effusion of a 53-year-old female with chronic myelogenous leukemia in terminal blast crises." - ATCC
Interferon gamma treatment - 30 minutes (Snyder)
IRF-1 (C-20) is an affinity purified rabbit polyclonal antibody raised against a peptide mapping at the C-terminus of IRF-1 of human origin. Antibody Target: IRF1
Interferon regulatory factor 1 is a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription and also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. IRF1 has been shown to play roles in regulating apoptosis and tumor suppression.