Sample information curated by ChIP-Atlas

Antigen

Antigen Class
TFs and others
Antigen
MAZ

Cell type

Cell type Class
Blood
Cell type
K-562
Primary Tissue
Blood
Tissue Diagnosis
Leukemia Chronic Myelogenous

Attributes by original data submitter

Sample

source_name
K562
biomaterial_provider
ATCC
lab
Stanford
lab description
Snyder - Stanford University
datatype
ChipSeq
datatype description
Chromatin IP Sequencing
cell
K562
cell organism
human
cell description
leukemia, "The continuous cell line K-562 was established by Lozzio and Lozzio from the pleural effusion of a 53-year-old female with chronic myelogenous leukemia in terminal blast crises." - ATCC
cell karyotype
cancer
cell lineage
mesoderm
cell sex
F
treatment
None
treatment description
No special treatment or protocol applies
antibody
MAZ_(ab85725)
antibody antibodydescription
Rabbit polyclonal, immunogen is synthetic peptide, corresponding to a region within amino acids 427-477 of Human MAZ, GenBank BAA33064.1. Antibody Target: MAZ
antibody targetdescription
May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors.
antibody vendorname
Abcam
antibody vendorid
ab85725
control
IgG-rab
control description
Input signal from Normal Rabbit IgG ChIP-seq.
control
IgG-rab
control description
Input signal from Normal Rabbit IgG ChIP-seq.
controlid
wgEncodeEH001795
replicate
1

Sequenced DNA Library

library_name
GSM935337: Stanford_ChipSeq_K562_MAZ_(ab85725)_IgG-rab
library_strategy
ChIP-Seq
library_source
GENOMIC
library_selection
ChIP

Sequencing Platform

instrument_model
Illumina Genome Analyzer

hg38

Number of total reads
56254723
Reads aligned (%)
97.0
Duplicates removed (%)
4.7
Number of peaks
47433 (qval < 1E-05)

hg19

Number of total reads
56254723
Reads aligned (%)
96.3
Duplicates removed (%)
5.8
Number of peaks
47179 (qval < 1E-05)

Base call quality data from DBCLS SRA