Sample information curated by ChIP-Atlas

Antigen

Antigen Class
TFs and others
Antigen
THAP1

Cell type

Cell type Class
Blood
Cell type
K-562
Primary Tissue
Blood
Tissue Diagnosis
Leukemia Chronic Myelogenous

Attributes by original data submitter

Sample

source_name
K562
biomaterial_provider
ATCC
datatype
ChipSeq
datatype description
Chromatin IP Sequencing
antibody antibodydescription
Goat polyclonal IgG, epitope mapping near the C-terminus of THAP1 of human origin. Antibody Target: THAP1
antibody targetdescription
The protein encoded by this gene contains a THAP domain, a conserved DNA-binding domain. This protein colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies, and functions as a proapoptotic factor that links PAWR to PML nuclear bodies. Alternatively spliced transcript variants encoding distinct isoforms have been observed. (provided by RefSeq)
antibody vendorname
Santa Cruz Biotechnology
antibody vendorid
sc-98174
controlid
SL2455
labexpid
SL2202,SL3186
replicate
1,2
softwareversion
MACS
antibody
THAP1_(SC-98174)
antibody antibodydescription
Goat polyclonal IgG, epitope mapping near the C-terminus of THAP1 of human origin.
antibody targetdescription
The protein encoded by this gene contains a THAP domain, a conserved DNA-binding domain. This protein colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies, and functions as a proapoptotic factor that links PAWR to PML nuclear bodies. Alternatively spliced transcript variants encoding distinct isoforms have been observed. (provided by RefSeq)
antibody vendorname
Santa Cruz Biotech
antibody vendorid
sc-98174
treatment
None
treatment description
No special treatment or protocol applies
protocol
v041610.1
protocol description
2x10^7 cells, fragmentation by bioruptor, one 15-cycle round of PCR (Myers)
controlid
SL2455
labexpid
SL2202
replicate
1
replicate description
tier 1

Sequenced DNA Library

library_name
GSM803408: HudsonAlpha_ChipSeq_K562_THAP1_(SC-98174)_v041610.1
library_strategy
ChIP-Seq
library_source
GENOMIC
library_selection
ChIP

Sequencing Platform

instrument_model
Illumina Genome Analyzer

hg19

Number of total reads
49792697
Reads aligned (%)
61.1
Duplicates removed (%)
21.7
Number of peaks
5798 (qval < 1E-05)

hg38

Number of total reads
49792697
Reads aligned (%)
61.7
Duplicates removed (%)
21.3
Number of peaks
5584 (qval < 1E-05)

Base call quality data from DBCLS SRA