Antigen

Antigen Class

TFs and others

Antigen

BCL3

Cell type

Cell type Class

Blood

Cell type

GM12878

Tissue

blood

Lineage

mesoderm

Description

B-lymphocyte, lymphoblastoid, International HapMap Project - CEPH/Utah - European Caucasion, Epstein-Barr Virus

Sample

source_name

GM12878

biomaterial_provider

GM12878

datatype

ChipSeq

datatype description

Chromatin IP Sequencing

cell description

B-lymphocyte, lymphoblastoid, International HapMap Project - CEPH/Utah - European Caucasion, Epstein-Barr Virus

antibody antibodydescription

Rabbit polyclonal. Bcl-3(C-14) is an affinity purified antibody raised against a peptide mapping at the C-terminus of Bcl-3 of human origin. Recommended for detection of Bcl-3 of mouse, rat and human origin by WB, IP, IF and ELISA. Antibody Target: BCL3

antibody targetdescription

This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. (Provided by RefSeq).

antibody vendorname

Santa Cruz Biotechnology

antibody vendorid

sc-185

controlid

SL1613

labexpid

SL3931,SL3728

replicate

1,2

softwareversion

MACS

antibody antibodydescription

Bcl-3(C-14) is an affinity purified rabbit polyclonal antibody raised against a peptide mapping at the C-terminus of Bcl-3 of human origin. Recommended for detection of Bcl-3 of m, r and h origin by WB, IP, IF and ELISA.

antibody targetdescription

This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. (Provided by RefSeq).

antibody vendorname

Santa Cruz Biotech

antibody vendorid

sc-185

treatment

None

treatment description

No special treatment or protocol applies

protocol

v041610.1

protocol description

2x10^7 cells, fragmentation by bioruptor, one 15-cycle round of PCR (Myers)

controlid

SL1613

labexpid

SL3728

replicate

1

replicate description

tier 1

Sequenced DNA Library

library_name

GSM803342: HudsonAlpha_ChipSeq_GM12878_BCL3_v041610.1

library_strategy

ChIP-Seq

library_source

GENOMIC

library_selection

ChIP

Sequencing Platform

instrument_model

Illumina Genome Analyzer

hg38

Number of total reads

66884656

Reads aligned (%)

86.7

Duplicates removed (%)

44.5

Number of peaks

24415 (qval < 1E-05)

hg19

Number of total reads

66884656

Reads aligned (%)

79.4

Duplicates removed (%)

41.2

Number of peaks

24886 (qval < 1E-05)