Antigen

Antigen Class

TFs and others

Antigen

Smarca4

Cell type

Cell type Class

Blood

Cell type

Th1 Cells

MeSH Description

A subset of helper-inducer T-lymphocytes which synthesize and secrete INTERLEUKIN-2; INTERFERON-GAMMA; and INTERLEUKIN-12. Due to their ability to kill antigen-presenting cells and their lymphokine-mediated effector activity, Th1 cells are associated with vigorous delayed-type hypersensitivity reactions.

Sample

source_name

Chromatin IP against BRG1, resting Th1

strain

BALB/c

cell type

resting Th1 CD4+ T helper cells

passages

differentiated in culture, single round, from Naïve cells

chip antibody

BRG (J1 antibody described in Genes Dev. 1996 Sep 1;10(17):2117-30, PubMed ID: 8804307)

Sequenced DNA Library

library_name

GSM585294: uTh1

library_strategy

ChIP-Seq

library_source

GENOMIC

library_selection

ChIP

Sequencing Platform

instrument_model

Illumina Genome Analyzer II

mm10

Number of total reads

8101441

Reads aligned (%)

39.8

Duplicates removed (%)

28.9

Number of peaks

4282 (qval < 1E-05)

mm9

Number of total reads

8101441

Reads aligned (%)

39.7

Duplicates removed (%)

29.4

Number of peaks

4250 (qval < 1E-05)